August Krogh Mini-symposium on glycogen regulation

August Krogh Club

Jørgen JensenGlycogen – more than an energy substrate

Professor Jørgen Jensen

NIH, Oslo, Norway.


Claude Bernard described glycogen in 1857, but quantitate determination was long challenging.

The studies by Bergström and Hultman in the late 1960ties indicated a link between glycogen depletion to fatigue, but most recent studies report substantial amount of skeletal muscle glycogen at exhaustion, and mechanisms linking glycogen depletion to fatigue are not well-documented.

The glycogen particle binds glycogen synthase and its activity associates with glycogen content, and regulatory mechanisms are being uncovered and explanations for glycogen supercompensation come closer.

August Krogh Club

Subcellular heterogeneity in muscle glycogen utilization during muscle work in vivo or with manipulation of specific ATPases in vitro

Joachim Nielsen

Associate Professor Joachim Nielsen

SDU, Odense, Denmark.


Within muscle fibres glycogen particles are stored in distinct subcellular compartments. The aim of this talk is to present recent findings on

1) how much glycogen is used from these distinct compartments during muscle work,

2) whether they impact endurance capacity, and

3) how the activity of myosin ATPases, Na+,K+-ATPases, and SR Ca2+ ATPases may influence this compartmentalized utilization of glycogen.


Intramyofibrillar glycogen drives endurance exercise capacity

Specific ATPases drive compartmentalized glycogen utilization in rat skeletal muscle


25 March 2022 14:00-16:00 CET (snacks and drinks will be served after the seminar)


Auditorium 1, August Krogh Building, Universitetsparken 13, DK-2100 Copenhagen


Participation is free, but please register here.

For PhD students

PhD students participating in August Krogh seminars receive 0,2 ECTS per seminar


Jens Frey Halling,

Jonas Møller Kristensen, 

Upcoming events

Link to other upcoming events.