PhD students participating in August Krogh seminars receive 0,2 ECTS per seminar
August Krogh Mini-symposium on glycogen regulation
August Krogh Club
Glycogen – more than an energy substrate
Professor Jørgen Jensen
NIH, Oslo, Norway.
Abstract
Claude Bernard described glycogen in 1857, but quantitate determination was long challenging.
The studies by Bergström and Hultman in the late 1960ties indicated a link between glycogen depletion to fatigue, but most recent studies report substantial amount of skeletal muscle glycogen at exhaustion, and mechanisms linking glycogen depletion to fatigue are not well-documented.
The glycogen particle binds glycogen synthase and its activity associates with glycogen content, and regulatory mechanisms are being uncovered and explanations for glycogen supercompensation come closer.
August Krogh Club
Subcellular heterogeneity in muscle glycogen utilization during muscle work in vivo or with manipulation of specific ATPases in vitro
Associate Professor Joachim Nielsen
SDU, Odense, Denmark.
Abstract
Within muscle fibres glycogen particles are stored in distinct subcellular compartments. The aim of this talk is to present recent findings on
1) how much glycogen is used from these distinct compartments during muscle work,
2) whether they impact endurance capacity, and
3) how the activity of myosin ATPases, Na+,K+-ATPases, and SR Ca2+ ATPases may influence this compartmentalized utilization of glycogen.
Literature
Intramyofibrillar glycogen drives endurance exercise capacity
Specific ATPases drive compartmentalized glycogen utilization in rat skeletal muscle
Time
25 March 2022 14:00-16:00 CET (snacks and drinks will be served after the seminar)
Venue
Auditorium 1, August Krogh Building, Universitetsparken 13, DK-2100 Copenhagen
Registration
Participation is free, but please register here.
For PhD students
PhD students participating in August Krogh seminars receive 0,2 ECTS per seminar
Contact
Jens Frey Halling, jefh@nexs.ku.dk
Jonas Møller Kristensen, jmkristensen@nexs.ku.dk
