AKC Seminar: Nightlife of the Brain

August Krogh Seminar

Professor Maiken Nedergaard M.D., D.M.Sc.

The Danish Society for Neuroscience Center for Translational Neuromedicine, University of Copenhagen, Denmark. 

The Glymphatic System

We have recently described a macroscopic pathway in the central nervous system – the glymphatic system that facilitates the clearance of interstitial waste products from neuronal metabolism. Glymphatic clearance of macromolecules is driven by cerebrospinal fluid (CSF) that flows in along para-arterial spaces and through the brain parenchyma via support from astroglial aquaporin-4 water channels.

The glymphatic circulation constitutes a complete anatomical pathway; para-arterial CSF exchanges with the interstitial fluid, solutes collect along para-venous spaces, then drain into the vessels of the lymphatic system for ultimate excretion from the kidney or degradation in the liver.  As such, the glymphatic system represents a novel and unexplored target for prevention and treatment of neurodegenerative diseases. 

Time

10 May 2019

14:00-15:00: Seminar and discussion
15:00-16:00: Post seminar servings and socializing

Venue

Auditorium 1, August Krogh Building, Universitetsparken 13, DK-2100 Copenhagen

Registration

Participation is free, but please register here.

For PhD students

PhD students participating in August Krogh seminars receive 0,2 ECTS per seminar

Contact

Jonas Møller Kristensen, jmkristensen@nexs.ku.dk 

Upcoming seminars

Link to other upcoming seminars.