PhD students participating in August Krogh seminars receive 0,2 ECTS per seminar
AKC Seminar: Protective Effects of Prior Exercise Training Against Acute Metabolic and Inflammatory Challenges
August Krogh Club Seminar
Associate Professor David Wright, PhD
Department of Human Health and Nutritional Sciences, University of Guelph, Canada.
Abstract
It is well known that adipose tissue inflammation plays an important role in the development of insulin resistance and diabetes. Exercise training has been extensively studied as a modality with which to treat and prevent inflammation. For instance, exercise training at the onset of a high fat diet prevents the development of inflammation and insulin resistance in rodents whereas training that is initiated after the onset of obesity leads to reductions in inflammation and improvements in glucose homeostasis. While these studies show a clear, beneficial effect of exercise on adipose tissue inflammation it is difficult to discern if the effects of exercise are direct or, are secondary to changes in adipose tissue mass. The purpose of this seminar will be to discuss recent work from my laboratory (both published and unpublished) and others, highlighting the protective effects of exercise against inflammatory and metabolic challenges.
Relevant papers
- Exercise training protects against an acute inflammatory insult in mouse epididymal adipose tissue. Laura Castellani, Jared Root-Mccaig, Scott Frendo-Cumbo, Marie-Soleil Beaudoin, David C. Wright
- Effects of exercise and low-fat diet on adipose tissue inflammation and metabolic complications in obese mice. Vieira VJ1, Valentine RJ, Wilund KR, Antao N, Baynard T, Woods JA.
- RPV4 is a regulator of adipose oxidative metabolism, inflammation and energy homeostasis. Li Ye, Bruce M. Spiegelman et al.
Research profile
Dr. Wright received his Bachelors Degree in Physical Education from the University of Calgary and then completed his PhD in Human Bioenergetics in the Human Performance Laboratory at Ball State University. Following his PhD Dr. Wright completed a postdoctoral fellowship in Dr. John Holloszy’ laboratory at Washington University School of Medicine. Dr. Wright is currently an Associate Professor in the Department of Human Health and Nutritional Sciences at the University of Guelph. His research is focused on understanding the effects of diet and exercise on adipose tissue and liver metabolism. His research program is funded by operating grants from the Canadian Institutes of Health Research, the Natural Sciences and Engineering Research Council of Canada and the Canada Research Chairs Program.
Time
23 January 2015
14:00-15:00: Seminar and discussion
15:00-15:30: Post seminar servings and socializing
Venue
Auditorium 1, August Krogh Building, Universitetsparken 13, DK-2100 Copenhagen
Registration
Participation is free, but please register here.
For PhD students
PhD students participating in August Krogh seminars receive 0,2 ECTS per seminar
Contact
Christian Frøsig, CFrosig@nexs.ku.dk, mobile +45 2875 1617
