August Krogh on Tour at AU: Adventures at the interface of endocrinology, metabolism and behaviour

Stephen O'Rahilly

Professor Sir Stephen O'Rahilly

August Krogh on Tour at Aarhus University

Adventures at the interface of endocrinology, metabolism and behaviour

Professor Sir Stephen O'Rahilly, Department of Clinical Biochemistry, University of Cambridge, United Kingdom.

Abstract

The recent increase in the proportion of the population with obesity and/or type 2 diabetes is a matter of great concern for global public health. The rising incidence of these disorders is clearly attributable to changes in the environment that promote caloric consumption and decrease energy expenditure. However we need to understand why some individuals are susceptible to obesogenic influences while others remain resistant.

Similarly, it would be helpful to have a better insight into the mechanises whereby some seriously obese people completely avoid the metabolic consequences of over-nutrition while others succumb to the disabling complications of metabolic derangement despite being only modestly obese.

In this lecture I will describe how human genetics has helped to enhance our understanding of our susceptibility or resistance to obesity and its adverse metabolic consequences. The findings have broad-ranging implications for the management of individual patients, for drug development and for public health strategies.

About the speaker

Stephen O’Rahilly’s research has been concerned with the elucidation of the fundamental mechanisms underlying obesity, insulin resistance and Type 2 diabetes and the translation of those discoveries into improvements in patient care.

His work has uncovered several previously unrecognised genetic causes of these diseases including some that are amenable to specific treatments. He is Co-Director of the Wellcome-MRC Institute of Metabolic Science (IMS), the establishment of which he led. Within the IMS, he is Director of the MRC Metabolic Diseases Unit and the Metabolic Research Laboratories of the University of Cambridge.

Time

25 May 2022 at 14:15 - 15:15. The talk will be followed by a reception.

Venue

AIAS Bygning 1632, 201, Høegh-Guldbergs Gade 6, 8000 Aarhus C, Danmark

Registration

No registration. You just show up.

Contact

Professor Niels Jessen, niels.jessen@biomed.au.dk

Upcoming events

Link to other upcoming events.


August Krogh on Tour is an event series where August Krogh Club will host internationally renowned physiologists for seminars in Copenhagen, Odense and Aarhus, and thereby bring together Danish and international research communities in celebration of August Krogh's legacy.